不同栓塞剂、不同栓塞水平经导管子宫动脉栓塞术后对血清性激素的影响

目的:探讨不同栓塞剂、不同栓塞水平在经导管子宫动脉栓塞术后对女性卵巢功能的影响。方法:对21例行子宫动脉栓塞术患者测定术前及术后3个月的血清雌激素(E2)、促卵泡成熟素(FSH)、黄体生成素(LH)水平。其中行子宫动脉栓塞术(UAE)18例,髂内动脉栓塞术(IIAE)3例;栓塞剂采用明胶海绵颗粒(GF)14例,PVA颗粒4例,超液态碘化油(lipodol)3例。结果:不同栓塞水平之间术后3个月血清三种性激素无明显差别,同一种栓塞水平于手术前后三种性激素无明显差别;不同栓塞剂之间术后3个月血清三种性激素无明显差别,同一种栓塞剂手术前后三种性激素无明显差别。结论:栓塞部位在高位的髂内动脉或是低位的子宫动脉,选用颗粒较粗的GF颗粒还是更加细小的PVA颗粒,对卵巢分泌功能影响小,不会对血清性激素产生不良影响。

Different embolization agents and position: impact on the level of sermn steroid hormones

Objective:To investigate the impact on the ovarian function after transcatheter arterial embolization (TAE) with different agents and position in uterine artery.Methods:Serum sex hormones of 21 cases performed TAE were measured in pre-operative and postoperative 3 months respectively. Among them, UAE were 18 cases and IIAE 3 cases; embolization agent were GF in 14 cases, PVA 4 cases, lipiodol 3 cases, respectively.Results:There was no significant difference in serum sex hormones between UAE and IIAE(P>0.05), no significant difference between embolization agents, and no significant between preoperative and postoperative cases.Conclusion:No matter the level of embolization, or the embolization agents, TAE for uterine has minimal impact on ovarian function, and most patients have on change in serum levels of sex hromones.