儿童静脉复合麻醉与局麻下肾活检的对比研究

目的 通过对儿童静脉复合麻醉经皮无痛肾活检与传统局麻下肾活检的成功率和安全性进行对比研究,探讨超声引导下无痛肾活检在儿童患者的临床应用意义.方法 将我科进行静脉复合麻醉无痛肾活检27例与传统局麻下肾活检23例患儿(均小于12岁)的临床与病理资料进行比较.观察两组的成功率(肾小球数大于15个或能够作出完整病理诊断为穿刺成功)和并发症.结果 无痛组患儿均顺利完成穿刺,肾小球数8～49(23.3±10.0)个;局麻组肾小球数0～40(23.2±9.4)个,2例无法配合放弃穿刺,2例肾小球数低于15个,无痛组和局麻组总成功率分别为96.3%和82.6%,具显著性差异.并发症:无痛组穿刺后麻醉苏醒时间为2～5 min,1例苏醒过程中发生呼吸抑制,加大吸氧和畅通呼吸道后好转,局麻组无麻醉并发症;肉眼血尿无痛组和局麻组各1例,肾周小血肿发生率分别为22.2%和21%,无显著性差异.结论 儿童静脉复合麻醉肾活检安全可靠,成功率高,其病理诊断对临床治疗及预后评价具有明确的指导意义,值得推广使用.

Kidney biopsy under traditional local or transient intravenous anesthesia:a comparative study in children

Objective To compare the successful rate and security of percutaneous renal biopsy under transient intravenous anesthesia and traditional local anesthesia in children. Methods Clinical and pathological data of children patients (less than 12 years old) undergoing ultrasound-guided renal biopsy with intravenous anesthesia from June 1, 2006 to May 30, 2007 in our department (Painless group) were compared with those of traditional local anaesthesia for renal biopsy from January 1, 1999 and May 30, 2006 (local ...