口腔颌面部恶性肿瘤6539例临床病理分析

目的:探讨口腔颌面部恶性肿瘤的发病情况及各类肿瘤的构成比。方法:对1953~2000年在华西医科大学口腔医院住院的经病理确诊的6539例口腔颌面部恶性肿瘤患者的临床资料进行回顾性分析。结果:患者平均年龄 4817岁;男女之比为2131B1;口腔、颌骨、涎腺分列口腔颌面部恶性肿瘤原发部位前3位;从组织来源分析,上皮源性肿瘤最多,有5869例(89175%),其次为淋巴造血系统肿瘤和间叶源性肿瘤等。从病理分型看,鳞状细胞癌4177 例(63188%),病例数较多者还有恶性淋巴瘤、粘液表皮样癌等。结论:口腔颌面部恶性肿瘤发病有增加的趋势,发病平均年龄有升高,男女比例逐渐下降,上皮源性肿瘤和鳞状细胞癌分列不同组织来源和病理类型肿瘤的首位。

A Retrospective Clinical Study of 6539 Cases of Malignant Oral-maxillofacial Tumors

OBJECTIVE: The aim of this study is to obtain the general information of post-operation malignant oral-maxillofacial tumor patients in forty-seven years. METHODS: A total of 6539 patients with malignant oral-maxillofacial tumors in the hospital of stomatology, west china university of medical sciences, from 1953 to 2000 were retrospected. RESULTS: The average age of patients with malignant oral-maxilloficial tumor is 48.7 years old. The ratio of male to female is 2.31:1. The most common original malignant tumors in this oral-maxillofacial region are malignant oral tumors, malignant maxillary tumors, malignant mandibular tumors, and malignant sialoma successively. As to the original tissues of tumors, there were 5869 cases of epithelial tumors, and made up 89.75% of all the investigated patients. Tumors came from lymphatic and hematopoietic systems and mesoderm were much less those came from epithelia. There were 4177 cases of squamous cell carcinomas and the percentage was 63.88%. CONCLUSION: The incidence rate of malignant tumors in oral-maxillofacial region tends to increase, and the average age of patients also rose. The ratio of male to female decreases gradually. Epithelial tumors, especially squamous cell carcinomas are very common tumors happening in this region.