Radiosensitivity of mouse lung cells measured using an in vitro colony method

We have detailed a method for the study of mouse lung cell clonogenicity in vitro, in which the average plating efficiency was 9%. When we used this method to study the inherent radiosensitivity of lung cells irradiated either in vivo or in vitro (18 hr after seeding), we found that the radiosensitivity of mouse lung cells was comparable to that of a large number of mammalian cell lines.