呼吸道病毒中耳感染与分泌性中耳炎发病的相关性研究

目的：探讨呼吸道病毒中耳感染与分泌性中耳炎发病的相关关系。方法：利用碱性磷酸酶抗碱性磷酸酶（alkaline phosphatase anti-alkaline phosphatase,APAAP)桥联酶标技术，检测分泌性中耳炎患者中耳积液所含脱落上皮细胞中的六种常见的呼吸道病毒抗原。结果：88例中耳积液中有65例（73．9％）检测到一种以上呼吸道病毒抗原，其中三例可同时检测到六种病毒抗原。发病前感冒史与抗原阳性率有明显相关性。结论：分泌性中耳炎患者中耳腔有多重病毒感染的可能，该病的发生与急性呼吸道感染有明显的关系。

Infection of Respiratiory Viruses and Secretony Otitis Media

Objective To discuss the relationship between the infection of respiratory viruses and secretory otitis media(SOM). Methods The alkaline phosphatase anti-alkaline phosphatase(APAAP) bridged rapid diagnosis was used to detect the antigens of the common respiratory viruses in middle ear effusions(MEES). Results One or more kinds of antigens of respiratory viruses were detected in 73.9% MEES. Six kinds of antigens were detected in three patients' MEES at the same time. There were significant differences positive rates of the antigens of respiratory viruses in MEES with or without a cold history(P <0.05). Conclusion Two or more viruses in the middle ear play a rule in the etiology of SOM. There is a relation between the occurrence of SOM and acute infection of respiratory tract.