电针治疗对急性脑梗死患者血清神经元特异性烯醇化酶及神经功能缺损的影响

目的通过观察电针对急性期脑梗死患者血清神经元特异性烯醇化酶(NSE)含量及神经功能缺损的影响,探讨电针对脑梗死的治疗作用和治疗时间窗。方法选择发病3d内的急性期脑梗死患者30例,随机分为对照组(常规药物治疗)和电针组(常规药物治疗加电针治疗2周),采用美国国立卫生研究院脑卒中量表(NIHSS)对患者进行神经功能缺损评分,观察2组患者治疗前、后血清NSE含量及NIHSS评分的变化。结果治疗前,2组血清NSE含量及NIHSS评分比较差异无统计学意义(P>0.05),治疗2周后,电针组NSE含量及NIHSS评分均明显低于对照组(P<0.05),且电针组NSE含量及NIHSS评分间存在显著相关性(r=0.781,P<0.01)。结论电针能够促进受损神经元的修复及神经功能缺损的恢复。

Effect of electroacupuncture on content of serum NSE and neurological dysfunction in patients with acute cerebral infarction

Objective To observe the effect of electroacupuncture (EA) on content of the serum neuronal specific enolase (NSE) and neurological dysfunction in patients with acute cerebral infarction. Methods Thirty patients with acute cerebral infarction (<3d) were divided randomly into two groups: an EA group (n=16) and a control group (n=14). Those in the EA group were treated by EA for two weeks in addition to the routine medications, while those in the control group only the routine medications. The NIHSS (National Institutes of Health Stroke Scale) was used to evaluate the level of neurological dysfunction. The content of serum NSE and scores of NIHSS were assessed before and after EA treatment, respectively. Results There were no significant differences with regard to the levels of NSE and scores of NIHSS between EA group and control group before treatment. While after two weeks of treatment, the levels of NSE and scores of NIHSS in the EA group were significantly lower than those of the control group (P<0.05). And the levels of NSE were closely related to the scores of NIHSS (r=0.781, P<~0.01) . Conclusion EA can effectively promote repair of neuron and recovery of the neurological dysfunction.