| 水飞蓟宾(Silybin)吸收系数的测定 |
| |
| 引用本文： | 蓝其田,康震,张时行,吴知行,于如嘏. 水飞蓟宾(Silybin)吸收系数的测定[J]. 中国药科大学学报, 1983, 0(1): 75-76 |
| |
| 作者姓名： | 蓝其田 康震 张时行 吴知行 于如嘏 |
| |
| 作者单位： | 南京药学院分析化学教研室，南京药学院分析化学教研室，江苏省药品检验所，南京药学院中草药化学教研室，南京药学院分析化学教研室 1982届毕业生 |
| |
| 摘 要： | 水飞蓟宾及其水溶性衍生物和制剂的含量测定系采用紫外分光光度法。为了简化分析手续和克服制备标准品的困难,有必要测定水飞蓟宾的百分吸收系数。据报道Bandarenko等的测定值为383±4.4,我们初次测定值为428.6。本文用进一步精制的水飞蓟宾纯品进行精密测定,其E_(1cm)~(1％)288nm值为456.1±1.8。一、条件选择 1.溶剂选择:分别以无水乙醇和95％乙醇作溶剂,对照试验表明:两者最大吸收波长288±1nm无改变,但所测得的吸收度明显下降,且溶解度不大理想,故仍采用无水乙醇作溶剂。
|
| 关 键 词： | 水飞蓟宾 百分吸收系数 |
DETERMINATION OF ABSORPTIVITY OF SILYBIN |
| |
| Lan Qitian,Kang Zhen,Zhang Shixing,Wu Zhixing and Yu Rugu. DETERMINATION OF ABSORPTIVITY OF SILYBIN[J]. Journal of China Pharmaceutical University, 1983, 0(1): 75-76 |
| |
| Authors: | Lan Qitian Kang Zhen Zhang Shixing Wu Zhixing Yu Rugu |
| |
| Affiliation: | Lan Chitien;Kang Zheng;Zhang Shixing;Wu Zhixing;Yu Rugu Division of Analytical Chemistry Graduate Student of 1982 Class Jiangsu Institute for Drug Control Division of Phytochemistry |
| |
| Abstract: | The assay of silybin has been successfully performed by UV spectrophotometry. The specific extinction coefficient (E 1%_1cm 288nm) has been measured to be 456.1 by using five different types of UV spectrophotometers. The results shows that the mean recovery is 99.88±0.48%, and the standard deviation is 0.58. |
| |
| Keywords: | Silybin Specific extinction coefficient |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中国药科大学学报》浏览原始摘要信息 |
|
点击此处可从《中国药科大学学报》下载全文 |
