家庭干预对抽动秽语综合征患儿生活质量的影响

目的调查家庭干预对抽动秽语综合征患儿生活质量的影响，评价家庭干预对抽动秽语综合征的治疗作用。方法将200例抽动秽语综合征患儿随机（随机数字法）分为观察组和对照组。观察组100例在常规治疗和护理的基础上实施为期1年的家庭干预，包括家庭教育、家庭访视和如何建立和谐家庭环境及健康生活方式的教育指导；对照组100例仅实施常规治疗和护理。治疗护理干预前后分别运甩耶鲁综合抽动严重程度量表、PedsQLTM4．0普适核心量表中文版、少儿主观生活质量问卷对患儿抽动严重程度，主观生活质量及部分功能进行问卷调查。结果1年后，在抽动次数、频率、强度、复杂性、干扰、损害方面观察组评分均低于对照组（￡分别为14．370，20．612，17．677，24．386，11．643，13．972；P均〈0．01）。家长报告生理功能、情感功能、社会功能、角色功能评分观察组分别为（90．78±11．32），（88．80±14．43），（76．78±11．3b），（66．80±14．53）分，对照组分别为（80．1±14．23），（58．10±13．32），（58．50±14．32），（52．80±13．15）分，各维度得分两组比较差异均有统计学意义（t分别为5．873，17．563，10．677，7．139；P均〈0．01）；儿童自我评价各维度差异也有统计学意义（t分别为5．967，9．946，7．071，7．379；P均〈0．01）。除躯体情感维度外，其余家庭生活、同伴交往、学校生活、生活环境、自我认识、抑郁体验、焦虑8个维度差异均有统计学意义（P〈0．01）。结论家庭干预治疗可明显提高抽动秽语综合征患儿的生存质量及人口素质。

Effects of family intervention on the life quality of children with tourette syndrome

Objective To explore and evaluate the effect of family intervention on quality of life of children with tourette syndrome. Methods Total of 200 children with tourette syndrome were randomly divided into observation group and control group. The observation group received conventional treatment and family intervention including family education, family visits and education guidance to build a harmonious family environment and healthy lifestyle, while the control group only received the conventional treatment and care. The therapeutic effects of both groups were assessed by Yale Global Tic Severity Scale （ YGTSS）, PedsQLTM 4.0 universal core scales score and Children＇ s subjective quality of life questionnaires. Results One year later, the frequency, intensity, complexity, interference, damage of spasm in the observation group were significantly lower than those of the control group （ t = 14. 370,20.612,17. 677,24. 386,11. 643,13. 972, respectively; P 〈 O. O1 ）. The average scores of families report in the observation group in physical function, mental function, social function, role function were（90.78 ± 11.32）, （88. 80 ± 14.43）, （76.78 ± 11.30）, （66.80 ± 14.53）, respectively, which were higher than （80.10 ± 14.23）, （58.10 ± 13.32）, （58.50 ± 14.32）, （52.80 ~ 13.15） in the control group, and the differences were statistically significant （ t = 5. 873,17. 563,10. 677,7. 139, respeetively;P 〈 0.01）. Each dimension score of childrdn self-evaluation in the observation group was significantly higher than that in the control group （P 〈0. 001 ）. There were significant differences in family life, companion contact, life environment, self-cognition, depress experience, anxiety, except the dimension of emotional body（P 〈 O. O1 ）. Conclusions Family intervention can significantly improve the quality of life and the quality of the population for children with tourette syndrome.