2008年安徽省阜阳市首起恙虫病暴发疫情的流行病学调查

目的对安徽省阜阳市首起恙虫病暴发疫情进行调查分析，以了解其流行病学特点和临床发病情况。方法应用《恙虫病个案调查表》对病例进行流行病学调查，通过外斐氏反应检测患者血清中的特异抗体进行诊断。结果本次暴发疫情共发现恙虫病病例78例。所有患者发病前均有野外暴露史，临床主要表现为发热、头痛、皮肤焦痂、皮疹和淋巴结肿大等，并发症较轻，经正确使用强力霉素治疗均有效缓解。结论该地区出现恙虫病暴发流行尚属首次报道。为针对性的预防和控制该地区恙虫病的发生和流行、保障野外劳作的安全提供了依据。强力霉素是治疗恙虫病的有效药物。

Epidemiological analysis on the first outbreak of tsutsugamushi disease in Fuyang City of Anhui Province in 2008

Objective To analyze the epidemiological and clinical characteristics of an outbreak of tsutsugamushi disease in Fuyang City of Anhui Province. Methods Epidemiological information was collected by case investigation questionnaire of tsutsugamushi disease. Diagnosis was determined by the detection of OXK antigen by Well-Felix test. Results Seventy-eight cases with tsutsugamushi disease were discovered in the outbreak. All the patients had an experience of working in this area before the starting of symptoms. The clinical features of the patients were fever, headache, skin eschar, tetter and lymphadenectasis. No severe complications occurred in each patient. All the patients recovered after getting deoxycycline. Conclusions This was the first report for the tsutsugamushi disease occurred in Fuyang City of Anhui Province. And the declaration for the new happened tsutsugamushi disease would provide strong support evidence for the prevention and control of this event and ensure the safety for working in this area. Also the deoxycycline was very effective for the treatment of tsutsugamushi disease.