| 严重肝病患者并发感染性休克外周血T淋巴细胞亚群的分析 |
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| 引用本文： | 刘远煌,陈万山,肖光明.严重肝病患者并发感染性休克外周血T淋巴细胞亚群的分析[J].实用肝脏病杂志,2007,10(6):389-390. |
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| 作者姓名： | 刘远煌 陈万山 肖光明 |
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| 作者单位： | 广州市第八人民医院肝病6区,510060 |
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| 摘 要： | 目的探讨并发感染性休克的肝病患者外周血T淋巴细胞亚群的变化。方法在42例并发感染性休克的慢性乙型肝炎患者,取外周血,采用特异性荧光抗体标记、BD流式细胞仪检测其T淋巴细胞亚群。结果慢性乙型肝炎并发感染性休克患者T淋巴细胞亚群表现为CD3 、CD4 、CD8 T淋巴细胞及CD4 /CD8 T比值明显下降(P<0.01),与无并发症组比较,CD3 、CD4 T淋巴细胞均明显下降(P<0.05),但CD8 T淋巴细胞无明显变化(P>0.05),导致CD4 /CD8 比值明显降低(P<0.05)。结论慢性乙型肝炎并发感染性休克患者T淋巴细胞亚群比无并发症组更紊乱,免疫功能更低下。
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| 关 键 词： | 乙型肝炎 感染性休克 T淋巴细胞亚群 外周血 |
| 收稿时间： | 2007-07-02 |
| 修稿时间： | 2007年7月2日 |
The analysis of peripheral blood T lymphocyte subsets in patients with severe hepatitis and infectious shock. |
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| LIU Yuanhuang,CHEN Wanshan,XIAO Guangming.The analysis of peripheral blood T lymphocyte subsets in patients with severe hepatitis and infectious shock.[J].Journal of Clinical Hepatology,2007,10(6):389-390. |
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| Authors: | LIU Yuanhuang CHEN Wanshan XIAO Guangming |
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| Abstract: | Objective To analysis the changes of peripheral blood T lymphocyte subsets in patients with chronic hepatitis B and infectious shock.Methods The T lymphocyte subsets were counted by flow cytometry with specific fluorescent antibody in 42 patients with hepatitis B and infectious shock.Results The counts of CD3 ,CD4 and CD8 T lymphocyte subsets and the ratio of CD4 / CD8 in patients with infectious shock dropped significantly (P<0.05), and the CD3 and CD4 cells with significantly lower than those in patients without shock, but the CD8 cells did not significantly decrease(P>0.05),while the ratio of CD4 / CD8 significantly decreased (P<0.05). Conclusion The cellular immunity of patients with hepatitis B and infectious shock is obviously damaged. |
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| Keywords: | Hepatitis B Infectious shock T lymphocyte subsets |
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