Disseminated Histoplasmosis Presenting as Weight Loss and Hypercalcemia in a Renal Transplant Patient With Prior History of Subtotal Parathyroidectomy |
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Authors: | Imran Gani Amanda Barrett Laura Mulloy Rajan Kapoor |
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Affiliation: | 1. Department of Nephrology, Hypertension and Transplant Medicine, Augusta University Health, Augusta, GA, United States;2. Department of Pathology, Augusta University Health, Augusta, GA, United States |
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Abstract: | Hypercalcemia and weight loss in a renal transplant patient especially with history of parathyroidectomy raises concern for an underlying malignancy, fungal infections or granulomatous disease. We present a case of 45-year-old male with history of subtotal parathyroidectomy presented with severe persistent hypercalcemia, acute kidney injury (AKI) and significant weight loss. An extensive workup revealed disseminated histoplasmosis. Hypercalcemia (which was refractory to initial medical management) and other symptoms resolved after a few weeks of initiating the antifungal treatment. |
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Keywords: | Corresponding author: Rajan Kapoor, MD, Augusta University Health 1120, 15th Street, AD 3401 Augusta University, Georgia USA 30912 Renal transplant Weight loss Hypercalcemia Acute kidney injury Histoplasmosis |
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