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Clinical Impacts of EGFR Mutation Status: Analysis of 5780 Surgically Resected Lung Cancer Cases
Authors:Kenichi Suda  Tetsuya Mitsudomi  Yasushi Shintani  Jiro Okami  Hiroyuki Ito  Takashi Ohtsuka  Shinichi Toyooka  Takeshi Mori  Shun-ichi Watanabe  Hisao Asamura  Masayuki Chida  Hiroshi Date  Shunsuke Endo  Takeshi Nagayasu  Ryoichi Nakanishi  Etsuo Miyaoka  Meinoshin Okumura  Ichiro Yoshino
Affiliation:1. Division of Thoracic Surgery, Department of Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan;2. Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, Suita, Japan;3. Department of General Thoracic Surgery, Osaka International Cancer Institute, Osaka, Japan;4. Department of Thoracic Surgery, Kanagawa Cancer Center, Yokohama, Japan;5. Division of Thoracic Surgery, Department of Surgery, Jikei University School of Medicine, Tokyo, Japan;6. Department of Thoracic Surgery, Okayama University Hospital, Okayama, Japan;7. Department of Thoracic Surgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan;8. Department of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan;9. Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Keio University, Tokyo, Japan;10. Department of General Thoracic Surgery, Dokkyo Medical University, Shimotsuga-gun, Japan;11. Department of Thoracic Surgery, Kyoto University, Kyoto, Japan;12. Department of Thoracic Surgery, Jichi Medical School, Shimotsuke, Japan;13. Department of Surgical Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan;14. Department of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan;15. Department of Mathematics, Tokyo University of Science, Tokyo, Japan;p. Department of General Thoracic Surgery, National Hospital Organization Toneyama Hospital, Toyonaka, Japan;q. Department of General Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan;1. Department of Thoracic Surgery, Peking University People’s Hospital, Beijing, China;1. Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan;2. Department of Thoracic Oncology, Aichi Cancer Center, Aichi, Japan;3. Department of Internal Medicine, Kinki-chuo Chest Medical Center, Osaka, Japan;4. Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan;5. Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Hyogo, Japan;6. Department of Respiratory Medicine, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan;7. Medical Sciences Department, Medical Affairs Division, Chugai Pharmaceutical Co., Ltd, Japan;8. Department of Thoracic Oncology, Osaka Habikino Medical Center, Osaka, Japan;9. Department of Respiratory Medicine, Osaka General Medical Center, Osaka, Japan;10. Department of Respiratory Medicine, Tohoku University Hospital, Miyagi, Japan;11. Department of Thoracic Oncology, Hyogo College of Medicine, Hyogo, Japan;12. Department of Respiratory Medicine, Kurashiki Central Hospital, Okayama, Japan;13. Department of Thoracic Oncology, National Hospital Organization, Toneyama National Hospital, Osaka, Japan;14. Division of Respiratory Medicine, Saiseikai Kumamoto Hospital, Kumamoto, Japan;15. Pulmonary Division, Department Internal Medicine, Saiseikai Utsunomiya Hospital, Tochigi, Japan;p. Department of Respiratory Medicine, Saiseikai Suita Hospital, Osaka, Japan;q. Department of Respiratory Medicine, Itami City Hospital, Hyogo, Japan;r. Third Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan;s. Department of Radiation Oncology, Kobe City Medical Center General Hospital, Hyogo, Japan;2. Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland;3. Frontier Science Foundation-Hellas & University of Athens, Athens, Greece;4. Aberdeen Royal Infirmary, Aberdeen, United Kingdom;6. Institute for Pathology, University Hospital Basel, Basel, Switzerland;5. Department of Oncology, University Hospital, Aarhus, Denmark;11. University Hospital KU Leuven, Leuven, Belgium;12. Vall d’Hebron University Hospital, Barcelona, Spain;8. Center of Predictive Molecular Medicine, University Foundation, Chieti, Italy;10. Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People''s Republic of China;9. VU University Medical Center, Amsterdam, Netherlands;112. Netherlands Cancer Institute, Amsterdam, Netherlands;123. Department of Medicine, University of Valencia and Department of Medical Oncology, General University Hospital of Valencia, Valencia, Spain;84. Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain;106. Clinic of Oncology, University Hospital Zurich, Zurich, Switzerland;1. Division of General Thoracic Surgery, Integrative Center of General Surgery, Gunma University Hospital, Maebashi, Gunma, Japan;2. Division of General Thoracic Surgery, Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano, Japan;3. Department of General Thoracic Surgery, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan;4. Department of Thoracic Surgery, Kyoto University, Kyoto, Kyoto, Japan;5. Division of General Thoracic Surgery, Shikoku Cancer Center, Matsuyama, Ehime, Japan;6. Division of General Thoracic Surgery, Chiba Cancer Center, Chiba, Chiba, Japan;7. Department of Thoracic Surgery, Kanagawa Cancer Center, Asahi-ku, Yokohama, Japan;8. Innovative Clinical Research Center, Kanazawa University, Kanazawa, Ishikawa, Japan;9. Department of Biostatistics, Hiroshima University Hospital, Hiroshima University, Hiroshima, Hiroshima, Japan;10. Department of Surgical Oncology, Hiroshima University, Hiroshima, Hiroshima, Japan;11. Department of General Thoracic Surgery, Dokkyo Medical University, Mibu, Tochigi, Japan;1. Department of Thoracic Surgery, Yamagata Prefectural Central Hospital, Yamagata, Japan;2. Department of Regenerative Surgery, Fukushima Medical University, Fukushima, Japan;3. Department of Pathology, Yamagata Prefectural Central Hospital, Yamagata, Japan;4. Department of Thoracic Surgery, Miyagi Cancer Center, Miyagi, Japan;5. Department of Endoscopy, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi, Japan;6. Department of Thoracic Surgery, Tohoku University Graduate School of Medicine, Miyagi, Japan;1. Multidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, Tennessee;2. Department of Thoracic Surgery, Hospital Universitari Mútua Terrassa, University of Barcelona, Terrassa, Spain;3. Network of Centers for Biomedical Research in Respiratory Diseases (CIBERES) Lung Cancer Group, Terrassa, Spain;4. University Health Network/Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada;5. Program in Solid Tumors, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain;6. Navarra Institute for Health Research (IdISNA), Pamplona, Spain;7. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain;8. Cancer Research and Biostatistics, Seattle, Washington;9. Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York;10. Division of Thoracic Surgery, Keio University School of Medicine, Tokyo, Japan;11. Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York;12. Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio;13. Center for Thoracic Oncology, Tisch Cancer Institute, Icahn School of Medicine, Mount Sinai Health System, New York, New York
Abstract:
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  • Keywords:Japanese Association for Chest Surgery
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