Medication compliance in long term phenprocoumon therapy |
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| Authors: | C. Van Gastel J. S. Meulenhoff G. S. Kraayenbrink-De Zeeuw S. J. Vles W. G. Zelvelder W. Knops |
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| Affiliation: | (1) Hervormd Diaconessenhuis, Van Lawick van Pabststraat 72, 6814 HK Arnhem, The Netherlands;(2) Thrombosis Service !["lsquo"]("/content/b85232p18q8621u7/xlarge8216.gif") Arnhem en Omstreken!["rsquo"]("/content/b85232p18q8621u7/xlarge8217.gif") , Boulevard Heuvelink 177, Arnhem, The Netherlands;(3) Formerly Department of Clinical Drug Research, TNO, Schoemakerstraat 97, Delft, The Netherlands;(4) Netherlands Institute for Educational Assessment, Oeverstraat 65, Arnhem, The Netherlands |
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| Abstract: | Medication compliance was assessed by a cross-sectional study of 225 patients, chosen at random from the records of a thrombosis service. The serum phenprocoumon concentration, in relation to the prescribed dose, was found to be unacceptably low in eleven patients. It is concluded that non-compliance occurs only infrequently. Thrombotest values were of little help in detecting non-compliance. |
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