| 两种伐昔洛韦抑制疗法方案预防生殖器疱疹复发作用比较 |
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| 引用本文： | 刘恩让,张书岭,王福喜,谢倩,刘姝丽. 两种伐昔洛韦抑制疗法方案预防生殖器疱疹复发作用比较[J]. 中国医院用药评价与分析, 2007, 7(4): 304-305 |
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| 作者姓名： | 刘恩让 张书岭 王福喜 谢倩 刘姝丽 |
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| 作者单位： | 深圳市第二人民医院皮肤科,深圳市,518035 |
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| 摘 要： | 目的:比较两种伐昔洛韦抑制疗法方案预防生殖器疱疹复发的临床效果。方法:将87例频发性生殖器疱疹患者(>3次/半年)随机分成2组,Ⅰ组42例患者口服万乃洛韦,300mg每日1次,。连续服用6个月。Ⅱ组45例患者口服万乃洛韦300mg,隔日1次,连续服用6个月。分别对用药前及用药6个月后的复发情况进行观察。结果:两种方案治疗后平均复发次数明显减少,但两组间平均复发次数差异无显著性(P>0.05)。结论:两种治疗方案对预防频发性生殖器疱疹复发疗效相同。
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| 关 键 词： | 生殖器疱疹 复发 伐昔洛韦 万乃洛韦 临床疗效 |
| 文章编号： | 1672-2124(2007)04-0304-02 |
| 修稿时间： | 2007-03-13 |
Two Valaciclovir Suppressive Therapies in Preventing Genital Herpes Recurrence |
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| LIU Enrang,ZHANG Shuling,WANG Fuxi,XIE Qian,LIU Shuli. Two Valaciclovir Suppressive Therapies in Preventing Genital Herpes Recurrence[J]. Evaluation and Analysis of Drug-Use in Hospital of China, 2007, 7(4): 304-305 |
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| Authors: | LIU Enrang ZHANG Shuling WANG Fuxi XIE Qian LIU Shuli |
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| Abstract: | OBJECTIVE: To compare the clinical efficacies of two Valaciclovir suppressive therapies in the prevention of genital herpes recurrence.METHODS: A total of 87 patients with recurrent genital herpes were randomly divided into two groups: group I(n=42) was assigned to receive oral Valaciclovir(at a dose of 300mg) q.d for 6 consecutive months,and group II(n=45) to receive Valaciclovir(at a dose of 300mg) every other day for 6 consecutive months.The recurrences in two groups were compared before medication and at 6 months after medication,respectively.RESULTS: The average number of times of recurrences of genital herpes were significantly decreased in both groups,but there was no significant difference between two groups(P>0.05).CONCLUSION: Two Valaciclovir suppressive therapies showed similar efficacy in the prevention of recurrent genital herpes. |
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| Keywords: | Genital herpes Recurrence Valaciclovir Valaciclovir Clinical efficacy |
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