| 非小细胞肺癌417例证候分布的临床研究 |
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| 引用本文： | 黎敬波,张征,林丽珠,马力,李科威,黎敬涛,白丽. 非小细胞肺癌417例证候分布的临床研究[J]. 广州中医药大学学报, 2009, 26(1) |
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| 作者姓名： | 黎敬波 张征 林丽珠 马力 李科威 黎敬涛 白丽 |
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| 作者单位： | 广州中医药大学基础医学院,广东广州,510405;福建中医学院,福建福州,350108;广州中医药大学第一附属医院,广东广州,510405;科凌力医学软件有限公司,广东深圳,518028;昆明理工大学,云南昆明,650093 |
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| 基金项目： | 国家自然科学基金，广东省中医药管理局课题 |
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| 摘 要： | [目的]研究非小细胞肺癌(NSCLC)的证候分布特点.[方法]采用前瞻性和回顾性相结合的流行病学研究方法,对确诊NSCLC适宜化疗、手术的群体进行西医治疗前后证候改变的抽样调查,将收集病例的症状(包括体征)进行赋值量化,数据输入数据库系统,将中医临床证候(症状)按照有关诊断标准进行归纳.[结果]NSCLC中以气虚痰热、气虚痰湿、痰热气滞血瘀、气阴两虚为主,分别占32.9%、30.0%、15.1%、13.4%.Ⅰ期与Ⅲ期、Ⅳ期证候比较,差异均有显著性意义(P<0.05).中医证候由气虚、痰热、痰湿、阴虚、气滞血瘀、阳虚6个基本因素组合而成.气虚因素最多占76.3%.痰热占52.8%,痰湿占33.8%,阴虚占18.2%,气滞血瘀占15.1%,阳虚最少仅占3.8%.舌象的相关系数值较其他症状高,表明舌象与证候相关性更明显.[结论]417例NSCLC的证候分布按比例多少排列为:气虚痰热>气虚痰湿>痰热气滞血瘀>气阴两虚>阴虚痰热>阳虚痰湿.气虚是NSCLC发生发展的内在根本原因,痰凝、气滞、血瘀为其主要病理变化.
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| 关 键 词： | 非小细胞肺癌/中医病机 肺肿瘤/中医病机 证候 |
Syndrome Patterns Distribution of Non-small-cell Lung Cancer: An Analysis of 417 Cases |
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| LI Jingbo,ZHANG Zheng,LIN Lizhu,MA Li,LI Kewei,LI Jingtao,BAI Li. Syndrome Patterns Distribution of Non-small-cell Lung Cancer: An Analysis of 417 Cases[J]. Journal of Guangzhou University of Traditional Chinese Medicine, 2009, 26(1) |
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| Authors: | LI Jingbo ZHANG Zheng LIN Lizhu MA Li LI Kewei LI Jingtao BAI Li |
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| Affiliation: | 1.College of Basic Medicine;Guangzhou University of TCM;Guangzhou 510405 Guangdong;China;2.Fujian College of TCM;Fuzhou 350108 Fujian;3.The First Affiliated Hospital;4.Kelingli Medical Software Ltd.Co;Shenzhen 518028 Guangdong;5.Kunming University of Science and Engineering;Kunming 650093 Yunnan;China |
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| Abstract: | Objective To investigate the syndrome patterns distribution of non-small-cell lung cancer(NSCLC).Methods Prospective and retrospective study methods were used for a sampling survey of the changes of syndrome patterns of confirmed NSCLC patients before and after chemotherapy and operation.The scores of symptoms and signs of the collected cases were input into the database.Subjecting to the clinical criteria of traditional Chinese medical syndromes,the symptoms and signs of NSCLC patients were classified.Resu... |
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