3D printing algorithm of anisotropic biological scaffold with oxidized nanocellulose and gelatin |
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Authors: | Xiaodong Xu Chen Feng Yani Jiang Qi Zhang Hongcan Shi |
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Institution: | 1. College of Animal Science and Technology, Yangzhou University, Yangzhou, China;2. Yangzhou Polytechnic Institute, Yangzhou, China;3. College of Mechanical Engineering, Yangzhou University, Yangzhou, China;4. Medical College of Yangzhou University, Yangzhou, China |
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Abstract: | AbstractTissue scaffolds need to have anisotropic mechanical properties and a porous structure to meet the needs of different tissues and organs. This report presents results of a study on an especially-designed 3D printing method with oxidized nanocellulose and gelatin, analyzes the servo principle of pneumatic condensing extrusion 3D printer, and proposes a hexagonal algorithm. For the purpose of this study, a printing process file was written by G code, physical and mechanical performance of the 3D scaffolds was evaluated with Solidworks simulation, the porous structure and pressure-pull performance of the printed 3D scaffolds was observed by SEM, and experiments were conducted to measure their bio-compatibility. The study draws the conclusion that scaffolds thus printed have a highly porous structure and anisotropic mechanical properties. |
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Keywords: | Tissue scaffold printing algorithm nanocellulose/gelatin anisotropy G code |
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