卒中后癫痫的临床观察

目的探讨卒中后癫痫的临床特点及发病机制。方法对1998年1月-2004年11月在我院住院的850例卒中病例中78例继发性癫痫患者的临床资料进行回顾性分析。结果卒中后癫痫的发病率为9.18％，早期癫痫发作6％，晚期癫痫发作318％，以部分性发作最多（61，54％）。卒中后癫痫的发生率与病灶部位（皮质／皮质下）有显著性差异（P〈0.05）。与卒中类型无明显差异（P〉0．05）。结论脑缺血缺氧是早期癫痫发作的重要致病因素。异常斑痕组织的形成等导致晚期癫痫发作。

Clinical observation of postapoplectic epilepsy

Objective] To evaluate the clinical features and pathogenesis of postapoplectic epilepsy. Method] A retrospective analysis of the clinical records of 78 eases of secondary epilepsy among the 850 patients who were hospitalized in our hospital from Jan.1998 to Nov.2004. Results] The attack rate of postapoplectic was 9.18%, and the rates of early and late epileptic attack were 6%and 3.18% respectively, among which partial attack reached to 61.54%. There was a significant difference between the attack rate of postapoplectic epilepsy and focal places-cortextand subcortext (P<0.05) and there was no significant diffevence between postapolectic epilespsy and apoplectic types (P>0.05). Conclusion] Ischemia and anoxia of brain is a vital pathogenic factor to early epileptic attack. The abnormal stigmatization causes late epileptic attack.