冠心病中医证型与心血管危险因素的相关性分析

目的研究冠心病各中医证型与多种心血管危险因素的相关性。方法采用流行病学方法调查456例患者,分别统计吸烟史,测血压、空腹血糖、血脂水平,与同期的健康体检者20例比较,分析中医证型与吸烟、高血压、空腹血糖及血脂的关系。结果中医证型以心血瘀阻证及痰阻心脉证为主。与对照组比较,冠心病各证型组吸烟、收缩压、舒张压、空腹血糖（FPG）均升高（P〈0.05）,其痰阻心脉证与吸烟关系最为密切（P〈0.05）,痰阻心脉证及气滞血瘀证均以收缩压及舒张压升高最为明显（P〈0.05）,FPG水平以气阴两虚证及心肾阴虚证升高为主（P〈0.05）。冠心病各证型组血脂TG、TC、LDL-C与对照组相比均升高,HDL-C降低（P〈0.05）,其中TG、TC以痰阻心脉证最高,阳气虚衰证最低（P〈0.05）;LDL-C以痰阻心脉证最高,气阴两虚证最低（P〈0.05）;HDL-C以气阴两虚证最低,气滞血瘀证最高（P〈0.05）。结论吸烟、血压、空腹血糖及血脂与冠心病中医证型存在相关性,可作为冠心病中医辨证分型辅助诊断的客观指标。

Correlation analysis of TCM syndrome with cardiovascular risk factors in coronary heart disease

Objective To research the correlation between traditional Chinese medicine （TCM） syndrome types of coronary heart disease （CHD） and multiple cardiovascular risk factors. Methods By adopting the method of epidemiological survey 456 cases of patients, separately summarize their smoking history, blood pressure, fasting plasma-glucose （FPG）, test blood lipid level, comparing the results with the homochromous 20 cases physical examination, then analyze the relations between Traditional Chinese Medicine （TCM） syndrome type with smoking, high blood pressure, fasting blood-glucose （FBG） and blood lipid. Results Syndrome of TCM mainly oriented with Heart blood stasis syndrome and Phlegm stasis syndrome. Compared with the control, smoking, systolic pressure, diastolic pressure and fasting plasma-glucose were increased in pts with coronary artery disease（ P 〈 0.05）. CHD in Phlegm stasis syndromehas the closest relation with Smoking（ P 〈 0.05） ; Systolic and diastolic blood pressure are most obvious at Phlegm stasis syndrome and Qi stagnation and blood stasis syndrome （ P 〈 0.05） ; The syndrome groups of CHD in FPG level with Qi and yin deficiency and Heart and kidney Yin deficiencysyndrome increased （ P 〈 0.05）. Triglycerides （TG）, total cholesterol （TC）, low-density lipoprotein-cholesterol （LDL-C） were increased in pts with coronary artery disease, High-density lipoprotein-cholesterol（HDL-C） decreased（ P 〈 0.05）. TG＆TC： Phlegm stasis syndrome is the highest one and Yang Qi deficiency syndrome is the lowest one（ P 〈 0.05 ）; LDL-C： Phlegm stasis syndrome is the highest one and Qi and Yin deficiency syndrome（ P 〈 0.05） ;HDL-C： Qi and Yin deficiency syndrome is the lowest one and Qi stagnation and blood stasis syndrome is the highest one（ P 〈 0.05）. Conclusion Smoking,hyper- tension,fasting plasma-glucose and blood lipid levels are correlated with the TCM syndrome types of CHD. They can be used as objective indexes to support the differ