Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA
Abstract:
High resolution prometaphase G-banding analysis was applied to three translocation carriers from the t(3;8) hereditary renal cell carcinoma family. It was clearly illustrated that the chromosomal rearrangement is reciprocal with breakpoints occurring at the subbands 3p14.2 (instead of 3p21) and 8q24.1.