| 复方口服避孕药与血脂异常 |
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| 引用本文： | 纪立伟,李可欣. 复方口服避孕药与血脂异常[J]. 药物不良反应杂志, 2011, 13(2): 90-94 |
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| 作者姓名： | 纪立伟 李可欣 |
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| 作者单位： | 卫生部北京医院药学部,北京,100730 |
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| 摘 要： | 复方口服避孕药(COC)为最常用的避孕制剂,其含有2种性激素:孕激素和雌激素.COC 可致心血管疾病.流行病调查显示COC引起的心血管疾病与血脂异常有关.其机制尚不完全清楚;三酰甘油水平的升高可能与肝脏分解脂肪和清除三酰甘油能力降低及血液中胰岛素水平增高有关.育龄期妇女长期使用时应尽可能交替使用不同种类的COC,用药期间进行血脂监测.
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| 关 键 词： | 复方口服避孕药 血脂异常 |
Combined oral contraceptives and dyslipidemia |
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| Ji Liwei,Li Kexin. Combined oral contraceptives and dyslipidemia[J]. Adverse Drug Reactions Journal, 2011, 13(2): 90-94 |
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| Authors: | Ji Liwei Li Kexin |
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| Affiliation: | Ji Liwei,Li Kexin (Department of Pharmacy,Beijing Hospital,Ministry of Public Health,Beijing 100730,China) |
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| Abstract: | Combined oral contraceptives are the most widely used contraceptives preparations,they contain two sex hormone: progestogen and estrogen.COC may cause cardiovascular diseases.Epidemiological evidence suggests that the dyslipidemia may be associated with these diseases.The mechanism of this phenomenon is not entirely clear;the elevation of blood triglyceride levels may be related to a decrease in lipolytic activity of liver and triglyceride removed as well as an increase in blood insulin levels.Different pre... |
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| Keywords: | combined oral contraceptive dyslipidemia |
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