| 儿童结核病101例临床分离结核分枝杆菌多位点串联重复序列分型 |
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| 引用本文： | 王均,黄延风,张爱华,许红梅.儿童结核病101例临床分离结核分枝杆菌多位点串联重复序列分型[J].第三军医大学学报,2011,33(13):1408-1410. |
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| 作者姓名： | 王均 黄延风 张爱华 许红梅 |
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| 作者单位： | 1. 重庆医科大学附属儿童医院:儿童发育疾病研究省部共建教育部重点实验室,重庆,400014
2. 重庆医科大学附属儿童医院:感染消化科,重庆,400014 |
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| 基金项目： | 重庆市科技计划项目(2008BB5389)~~ |
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| 摘 要： | 目的 了解重庆地区儿童结核病中结核分枝杆菌临床分离株的数目可变串联重复序列(variable number tandem repeats,VNTR)的分布特征,寻找适合的VNTR位点组合.方法 采用多位点串联重复序列(multiple locus VNTR analysis,MLVA)分型方法,选择标化的24个VNTR...
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| 关 键 词： | 结核分枝杆菌 多位点可变数目串联重复序列 基因分型 |
Genotyping of 101 Mycobacterium tuberculosis isolates from pediatrics tuberculosis in Chongqing by multiple locus VNTR analysis |
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| Wang Jun,Huang Yanfeng,Zhang Aihua,Xu Hongmei.Genotyping of 101 Mycobacterium tuberculosis isolates from pediatrics tuberculosis in Chongqing by multiple locus VNTR analysis[J].Acta Academiae Medicinae Militaris Tertiae,2011,33(13):1408-1410. |
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| Authors: | Wang Jun Huang Yanfeng Zhang Aihua Xu Hongmei |
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| Institution: | Wang Jun1,Huang Yanfeng2,Zhang Aihua2,Xu Hongmei2(1Key Laboratory of Developmental Diseases in Childhood Cofounded by Chongqing and Ministry of Education,2Department of Infection and Digestion,Children's Hospital,Chongqing Medical University,Chongqing,400014,China) |
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| Abstract: | Objective To study the distribution of the variable number tandem repeats(VNTR) in clinically isolated strains Mycobacterium tuberculosis(M.tuberculosis) from pediatrics tuberculosis in Chongqing and explore the effective loci combination of them by multiple locus VNTR analysis(MLVA).Methods Twenty-four standardized MLVA loci was used to type the 101 clinically isolated M.tuberculosis strains,and the results were analyzed by BioNumerics 6.1 software,which including dendrogram and Hunter-Gaston index(HGI) of... |
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| Keywords: | Mycobacterium tuberculosis multiple locus variable number tandem repeats analysis genotyping |
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