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Effects of forssman antibody on renal function of the guinea pig |
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| Authors: | J. E. Barbosa W. Sarti G. B. Mello |
| Affiliation: | 1. Dept. of Parasitology, Microbiology, and Immunology, University of S?o Paulo, 14.049, Ribeir?o Preto, SP-Brazil 2. Dept. of Internal Medicine, University of S?o Paulo, 14.049, Ribeir?o Preto, SP-Brazil 3. Dept. of Physiology Medical School of Ribeir?o Preto, University of S?o Paulo, 14.049, Ribeir?o Preto, SP-Brazil |
| Abstract: | When guinea pigs were injected with rabbit anti-sheep red blood cell antiserum (Forssman antibody) by the intra arterial (i.a.) route (abdominal aorta at the level of the renal arteries), they developed renal disfunction. A diminished glomerular filtration rate associated with a 27% increase in the fractional excretion of K+ was observed. No alterations were noted in the fractional excretion of water and NA+. |
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