| γ线局部照射后大鼠胰淀粉酶胰蛋白酶活性变化 |
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| 引用本文： | 薛宝刚,张云祥. γ线局部照射后大鼠胰淀粉酶胰蛋白酶活性变化[J]. 军事医学科学院院刊, 1988, 0(4) |
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| 作者姓名： | 薛宝刚 张云祥 |
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| 作者单位： | 军事医学科学院放射医学研究所，军事医学科学院放射医学研究所 |
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| 摘 要： | 本文观察了大鼠上腹部局部γ线照射后胰淀粉酶、胰蛋白酶活性.结果表明,腹部局部照射后这些酶的活性明显降低.在一定剂量范围内,随照射剂量增加胰酶活性逐步降低.γ线30Gy腹部分次照射后第5天胰淀粉酶、胰蛋白酶活性降低到正常的60%左右,并长期处于较低的活性水平.照后90～120天两种酶的活性恢复到正常水平.照射后胰腺腺泡细胞的超微结构变化支持上述实验结果.以上结果提示,腹部局部照射可导致胰腺外分泌功能障碍,至于局部照射后胰外分泌酶活性降低及其恢复的机制尚待进一步探讨.
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| 关 键 词： | 胰淀粉酶活性 胰蛋白酶活性 胰腺外分泌 |
THE CHANGES OF AMYLASE AND TRYPSIN ACTIVITIES IN RAT AFTER ABDOMEN GAMMA IRRADIATION |
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| Xue Baogang,Zhang Yuenxiang Institute of Radiation Medicine,Academy of Military Medical Sciences. THE CHANGES OF AMYLASE AND TRYPSIN ACTIVITIES IN RAT AFTER ABDOMEN GAMMA IRRADIATION[J]. Bulletin of the Academy of Military Medical Sciences, 1988, 0(4) |
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| Authors: | Xue Baogang Zhang Yuenxiang Institute of Radiation Medicine Academy of Military Medical Sciences |
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| Abstract: | The changes of amylase and trypsin activities in rat following local abdomen gamma irradiation were studied.The results showed that within a certain dose range,the activities of pancreatic enzymes decreased with the increase of doses and reached half of the normal value five days after local and fractional radiation with 30Gy on the abdomen,and maintained at level below normal for a long time.The complete recovery of pancreatic enzyme activities occurred 120 days after local abdomen exposure.The mechanism of the decrease and recovery of pancreatic enzyme activity after exposure to radiation is briefly discussed. |
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| Keywords: | amylase activity trypsin activity exocrine secretion of pancreas |
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