Absence of a prosthetic group in a type-specific polysaccharide of pneumococcus |
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Authors: | HEIDELBERGER M MacLEOD C M MARKOWITZ H DiLAPI M M |
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Institution: | From the Department of Medicine, College of Physicians and Surgeons, Columbia University, and the Department of Microbiology, New York University College of Medicine, New York |
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Abstract: | The specific polysaccharide of Type III pneumococcus, with only 0.05 per cent of N and 0.01 per cent of P, still shows almost maximal precipitation of a Type III antipneumococcus rabbit serum and the expected antigenicity in man. There is therefore no evidence that a prosthetic group is involved in these characteristic activities. |
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