| 甲状腺功能亢进并周期性麻痹的发病机制探讨 |
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| 引用本文： | 高鹏霞,吕述军,胡长军. 甲状腺功能亢进并周期性麻痹的发病机制探讨[J]. 徐州医学院学报, 2005, 25(2): 133-134 |
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| 作者姓名： | 高鹏霞 吕述军 胡长军 |
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| 作者单位： | 南京医科大学附属淮安市第一人民医院内分泌科,江苏,淮安,223300 |
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| 摘 要： | 目的探讨甲状腺功能亢进(甲亢)并周期性麻痹的发病机制。方法15例男性甲亢并周期性麻痹的Graves病患者与15例男性甲亢非周期性麻痹的Graves病患者行临床对比分析，比较其一般情况，测定其FB、Fr4、s-TSH、空腹血糖(FBG)、餐后2h血糖(2h PBG)、空腹胰岛素(FINS)，计算胰岛素敏感指数(QUICKI)。结果甲亢并周期性麻痹组QUICKI指数明显低于甲亢非周期性麻痹组，空腹胰岛素水平明显高于甲亢非周期性麻痹组。结论胰岛素抵抗可能为甲亢患者发生周期性麻痹的原因之一。
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| 关 键 词： | 甲状腺功能亢进 周期性麻痹 机制探讨 Graves病 空腹血糖（FBG） 胰岛素敏感指数 临床对比分析 餐后2h血糖 s-TSH 空腹胰岛素 胰岛素水平 胰岛素抵抗 发病机制 甲亢患者 Fr4 男性 |
| 文章编号： | 1000-2065(2005)02-0133-02 |
The pathogenesis of hyerthyroidism associated with periodic paralysis |
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| GAO Peng-xia,LU Shu-jun,HU Chang-jun. The pathogenesis of hyerthyroidism associated with periodic paralysis[J]. Acta Academiae Medicinae Xuzhou, 2005, 25(2): 133-134 |
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| Authors: | GAO Peng-xia LU Shu-jun HU Chang-jun |
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| Abstract: | Objective To study the pathogenesis of hyerthyroidism associated with periodic paralysis.Methods 15 male patients suffering from hyperthyroidism associated with periodic paralysis and another 15 ordinary hperthyroidism male patients were assigned to undergo a comparative study. The levels of FT_3, FT_4, s-TSH, FBG,2 h PBG and FINS were determined,the quantitative insulin sensitivity check index (QUICKI) was calculated.Results The QUICKI was significantly lower and the FINS level was significantly higher in the patients with hyperthyroidism associated with periodic paralysis than in the controls.Conclusion Insulin resistanc e might be one cause of the periodic paralysis in hyperthyroidism patients. |
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| Keywords: | hyperthyroidism periodic paralysis insulin resistance |
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