Novel salicylamide derivatives incorporating neonicotinoid pharmacophore: design, synthesis, characterization, and biological evaluation |
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| Authors: | Shaoyong Ke Zhigang Zhang Tong Long Ying Liang Ziwen Yang |
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| Affiliation: | 1. National Biopesticide Engineering Research Center, Hubei Academy of Agricultural Sciences, Wuhan, 430064, People’s Republic of China
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| Abstract: | A series of novel salicylamide derivatives containing neonicotinoid pharmacophore were designed and synthesized via multi-step reactions. These compounds were characterized by satisfied spectrum analyses mainly including 1H NMR and ESI-MS. The preliminary bioassays indicated that some of target compounds exhibited excellent insecticidal activities against Heliothis armigera and Plutella xylostella at the dosage of 31.25 μg/mL. |
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