Anti-platelet aggregating and anti-oxidative activities of 11-O-(4'-O-methylgalloyl)-bergenin, a new compound isolated from Crassula cv. 'Himaturi' |
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Authors: | Lee Yong Yook Jang Dae Song Jin Jing Ling Yun-Choi Hye Sook |
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Institution: | Natural Products Research Institute, Seoul National University, Seoul, Korea. |
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Abstract: | A new compound, 11- O-(4'- O-methylgalloyl)-bergenin was isolated from the MeOH extract of Crassula cv. 'Himaturi'. The structure of the compound was determined on the basis of chemical and spectroscopic data. It inhibited arachidonic acid-induced platelet aggregation more efficiently than acetylsalicylic acid and showed an anti-oxidative effect (EC (50) = 23.9 microM) equivalent to that of L-ascorbic acid or quercetin. |
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