| 高效液相色谱法测定咽炎片中没食子酸含量 |
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| 引用本文： | 王维礼,付利,程晓英. 高效液相色谱法测定咽炎片中没食子酸含量[J]. 中国药业, 2008, 17(11): 30-31 |
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| 作者姓名： | 王维礼 付利 程晓英 |
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| 作者单位： | 1. 吉林省吉林市食品药品检验所,吉林,吉林,132001
2. 吉林省吉林市职业病医院,吉林,吉林,132001 |
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| 摘 要： | 目的建立咽炎片的含量测定方法。方法采用高效液相色谱（HPLC）法，以乙腈-含0．1％三乙胺的0．1％磷酸溶液（1：99）为流动相，检测波长为273nm。结果没食子酸质量浓度在0．010-0．050mg／mL范围内与峰面积线性关系良好（r=1．0000）；平均加样回收率为99．19％，RSD=1．0％（n=6）。结论HPLC法简便易行，结果准确可靠，可用于咽炎片的质量控制。
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| 关 键 词： | 高效液相色谱法 咽炎片 没食子酸 含量测定 |
| 文章编号： | 1006-4931(2008)11-0030-02 |
| 修稿时间： | 2007-07-04 |
Determination of Gallic Acid in Yanyan Tablets by HPLC |
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| Wang Weili,Fu Li,Cheng Xiaoying. Determination of Gallic Acid in Yanyan Tablets by HPLC[J]. China Pharmaceuticals, 2008, 17(11): 30-31 |
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| Authors: | Wang Weili Fu Li Cheng Xiaoying |
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| Affiliation: | Wang Weili, Fu Li, Cheng Xiaoying ( 1. Jilin Institute for Food and Drug Control, Jilin, Jilin, China 132001; 2. The Hospital for Industrial Disease Prevention and Cure of Jilin City, Jilin, Jilin, China 132001) |
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| Abstract: | Objective To set up a method for quality control of Yanyan Tablets. Methods HPLC method was used for quantitative determination. The mobile phase was acetonitrile-0. 1% phosphoric acid solution containing 0.1% triethylamine （1：99）.The wavelength for detection was 273 nm. Results A good linearity was abtained in the concentration range of 0. 010-0. 050 mg/mL for gallic acid （r= 1. 000 0）. The average recovery rate was 99.19% ,and RSD was 1.0% （n =6）. Conclusion The method is simple,accurate and suitable for its quality control. |
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| Keywords: | HPLC Yanyan Tablets gallic acid determination |
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