CRP、ESR在儿童感染性疾病诊断中的意义

目的:探讨血清中C反应蛋白(CRP)、血沉(ESR)的检测对儿童早期感染鉴别诊断的价值。方法:检测感染儿童82例及体检儿童15例的血常规、血沉、及血清中C反应蛋白的含量。结果:细菌感染组与病毒感染组、对照组比较,CRP、WBC明显升高,差异性显著(P<0.001)。细菌感染组与病毒感染组ESR均升高,但细菌感染组升高明显些。CRP与ESR相比,CRP的特异性及灵敏性都较ESR好。结论:小儿急性感染时,CRP、WBC、ESR的检测有助于疾病早期的鉴别诊断,对于细菌性感染和病毒性感染的鉴别诊断有一定的价值。

Significance of CRP and ESR in Diagnosis of Children's Infectious Diseases

Objective To explore the value of detecting Erythrocyte sedimentation rate(ESR) and C-reactive protein(CRP) in children for differential diagnosis of early infection.Methods Blood routine,ESR and the content of CRP in serum were detected,which in 82 infected children and 15 normal children for health examination.Results The CRP and WBC in the bacterial infection group dramatically step up with statistically significant difference(P<0.001),in comparison with which in the viral infection and control group.ESR of bacterial group and that of viral group all step up,but the former does dramatically.CRP is better than ESR in specificity and sensitivity.Conclusion In children's acute infection,detection of CRP,ESR and White cell count is helpful to differential diagnosis of diseases at early stage,and it is of some value in differential diagnosis between the bacterial and viral infection.