Kikuchi-Fujimoto's disease: report of 5 cases and literature review] |
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| Authors: | D Adjaoud S Boudjemaa L Boccon-Gibod G Leverger |
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| Affiliation: | 1. Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Hyderabad, India;2. Department of Gastroenterology, Gandhi General Hospital, Secunderabad, India;3. Department of Gastroenterology, Osmania General Hospital, Hyderabad, India;4. Department of Genetics, Osmania University, Hyderabad, India;1. College of Plant Protection of Hunan Agricultural University, Changsha 410128, PR China;2. Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China;3. Department of Entomology, University of Kentucky, Lexington, KY 40546-0091, USA |
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| Abstract: | Kikuchi-Fujimoto's disease or histiocytic necrotizing lymphadenitis is a benign disease predominantly occurring in young women which etiology remains unknown and revealed by cervical lymphadenitis and/or prolonged fever. It has rarely been reported in children. Among the 5 cases reported, 1 child had a systemic localization. The diagnosis is based on the histological examination of a lymph node biopsy. The disease course was spontaneously favourable in 2 cases; a corticotherapy was needed in 3 children. A pathogen agent was found in 2 patients. Kikuchi's disease can reveal or evolve into autoimmune disease particularly lupus, thus a long clinical and biological follow-up is necessary. |
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