| 尖锐湿疣患者细胞免疫功能和血清可溶性粘附分子水平研究 |
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| 引用本文： | 张谊之,张敏,李俸媛. 尖锐湿疣患者细胞免疫功能和血清可溶性粘附分子水平研究[J]. 临床皮肤科杂志, 2002, 31(9): 555-556 |
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| 作者姓名： | 张谊之 张敏 李俸媛 |
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| 作者单位： | 1. 四川大学华西医院皮肤性病科,四川,成都,610041
2. 四川大学华西医院病理科,四川,成都,610041 |
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| 基金项目： | 四川省卫生厅科研项目资助课题 |
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| 摘 要： | 为了解尖锐湿疣(CA)患者的细胞免疫功能和血清可溶性粘附分子水平,采用ELISA方法检测了33例CA患者血清中IL-2及其可溶性受体(sIL-2R)、IL-6、可溶性细胞间粘附分子-1(sICAM-1)和血管细胞粘附分子-1(sVCAM-1)水平。结果发现患者血清中IL-2及IL-6水平明显低于正常对照(P<0.01),sIL-2R、sICAM-1、sVCAM-1明显高于对照(P<0.05),提示CA患者存在细胞免疫缺陷和血清高粘附分子水平。
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| 关 键 词： | 细胞免疫功能 ELISA IL－2 尖锐湿疣 可溶性细胞间粘附分子－1 血管细胞粘附分子－1 |
| 文章编号： | 1000-4963(2002)09-0555-02 |
| 修稿时间： | 2002-01-12 |
Observation of cellular immunity levels and seral adhesion molecules in patients with condyloma acuminatum |
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| ZHANG Yi-zhi,ZHANG Min,LI Feng-yuan. Observation of cellular immunity levels and seral adhesion molecules in patients with condyloma acuminatum[J]. Journal of Clinical Dermatology, 2002, 31(9): 555-556 |
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| Authors: | ZHANG Yi-zhi ZHANG Min LI Feng-yuan |
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| Abstract: | To investigate the levels of cellular immunity and seral ahesion molecules in patients with condyloma acuminatum(CA),the levels of IL-2,sIL-2R,IL-6,sICAM-1and sVCAM-1were measured in33patients with CA by ELISA.The results showed that seral levels of IL-2and IL-6were significantly lower in patients than in normal controls(P<0.01),and levels of sIL-2R,sICAM-1,sVCAM-1were significantly higher(P<0.05).It suggested that there were cellular immunity deficiency and high seral level of adhesion molecules in CA patients. |
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| Keywords: | condyloma acuminatum IL-2 sIL-2R IL-6 sICAM-1 sVCAM-1 |
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