| 同型半胱氨酸等在2型糖尿病肾损伤诊断中的应用 |
| |
| 引用本文： | 陈茹. 同型半胱氨酸等在2型糖尿病肾损伤诊断中的应用[J]. 基层医学论坛, 2008, 12(28): 865-867 |
| |
| 作者姓名： | 陈茹 |
| |
| 作者单位： | 徐州市第一人民医院,江苏,徐州,221002 |
| |
| 摘 要： | 目的探讨血清hs-CRP、Hcy和Mau在2型糖尿病患者中的变化。方法58例健康者作为正常对照组,144例2型糖尿病患者分为65例不伴糖尿病肾病(DM组)和79例伴糖尿病肾病(DN组)。应用免疫散射比浊法测定各组血清hs-CRP水平及24hMau,采用化学发光法测定血清Hcy,比较3组间差异。结果Mau(mg/24h)正常对照组12.73±5.89;DM组41.65±16.31;DN组226.92±45.22。血清hs-CRP(mg/L)正常对照组2.90±1.86;DM组5.79±3.27;DN组11.01±5.06。血清Hcy(μmol/L)正常对照组7.41±1.32;DM组8.43±1.36;DN组12.31±1.95。2型糖尿病患者hs-CRP、Hcy、Mau水平明显高于正常对照组,而糖尿病肾病患者值又明显高于无肾损伤患者。结论DN患者血清Hcy和CRP水平随着Mau的增加而升高,提示两者可能与DN的进展有关,随着肾脏损害的加重而逐步升高,可能是糖尿病肾病的一个新的危险因素。可以作为预测糖尿病肾损伤及肾损害程度的指标。
|
| 关 键 词： | 糖尿病 肾脏损伤 超敏C反应蛋白 同型半胱氨酸 微量白蛋白 |
Clinical application of high sensitive C -reactive protein homocysteic acid and urinary microalbum level in diagnosing for type 2 diabetic patients with diabetes nephropathy |
| |
| Chen Ru. Clinical application of high sensitive C -reactive protein homocysteic acid and urinary microalbum level in diagnosing for type 2 diabetic patients with diabetes nephropathy[J]. Public Medical Forum Magazine, 2008, 12(28): 865-867 |
| |
| Authors: | Chen Ru |
| |
| Affiliation: | Chen Ru.Department of Medical Laboratory; The first people’s Hospital of Xuzhou; Jiangsu; 221002; |
| |
| Abstract: | Objective To explore the changes of serum high sensitive C-reactive protein(hs-CRP) homocysteic acid(Hcy) and microalbuminuria(Mau)level in type 2 diabetes and to investigate its clinical significance in diabetes nephropathy.Methods 58 healthy individuals were chosen as normal controls,144 patients with type 2 diabetes mellitus were divided into 65 Type 2 diabetic patients without diabetic nephropathy(DM)and 79 Type 2 diabetic patients with nephropathy(DN)for this study.The serum hs-CRP and Mau concentratio... |
| |
| Keywords: | Diabetes mellitus Diabetic nephropathy High sensitive C-reactive protein Homocysteic acid Micro albuminuria |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
