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Persistent normalization of serum levels of uric acid in a gouty patient after administration of cyproterone acetate
Authors:C. Palazzi  S. D’Angelo  E. Pennese  I. Olivieri
Affiliation:(1) Division of Rheumatology, “Villa Pini” Clinic, Chieti, Italy;(2) Rheumatology Department of Lucania, “S. Carlo” Hospital of Potenza and “Madonna delle Grazie” Hospital of Matera, Potenza, Italy;(3) Via Legnago 23, 65123 Pescara, Italy
Abstract:In this article we describe a gouty caucasian male patient who had high levels of serum uric acid since 1970s. Serious adverse reactions to allopurinol discouraged its administration. We prescribed cyproterone acetate (CA) because of severe prostatic hypertrophy, associated with a suspect small cancer. The administration of this drug obtained persistent normalization of serum uric acid levels. Our observation, that needs to be confirmed in other cases, could suggest a possible new treatment for gout in male patients with prostatic disorders.
Keywords:Androgens  Cyproterone  Gout  Prostate  Uric acid
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