| 药用辅料羟丙基甲基纤维素在制剂中的应用 |
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| 引用本文： | 武慧超,杜守颖,陆洋,黎迎,李鹏跃,陈振振. 药用辅料羟丙基甲基纤维素在制剂中的应用[J]. 中国实验方剂学杂志, 2013, 19(17): 360-365 |
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| 作者姓名： | 武慧超 杜守颖 陆洋 黎迎 李鹏跃 陈振振 |
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| 作者单位： | 北京中医药大学中药学院,北京,100102 |
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| 基金项目： | 国家自然科学基金面上项目(81073057);北京中医药大学创新团队发展计划(2011-CXTD-13);国家自然科学基金青年基金项目(81102816) |
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| 摘 要： | 查阅药用辅料羟丙基甲基纤维素(HPMC)在制剂中近年来国内外相关文献,进行分析、归纳,阐述它在固体制剂、液体制剂、缓控释制剂、胶囊制剂、凝胶制剂以及生物黏附剂等新型制剂领域的最新应用.因HPMC相对分子量和黏度的不同,具备乳化、黏合、增稠、增黏、助悬、胶凝和成膜等特点和用途,广泛应用于药物制剂中,在制剂领域将发挥更大作用.随着对其性质研究的深入以及制剂技术的提高,HPMC将更大量应用于新剂型、新给药系统的研究中,进而推动制剂学的不断发展.
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| 关 键 词： | 羟丙基甲基纤维素 药物制剂 药剂辅料 |
| 收稿时间： | 2012-11-27 |
Application of Pharmaceutical Excipients Hydroxy Propyl Methyl Cellulose in Preparation |
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| WU Hui-chao,DU Shou-ying,LU Yang,LI Ying,LI Peng-yue and CHEN Zhen-zhen. Application of Pharmaceutical Excipients Hydroxy Propyl Methyl Cellulose in Preparation[J]. China Journal of Experimental Traditional Medical Formulae, 2013, 19(17): 360-365 |
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| Authors: | WU Hui-chao DU Shou-ying LU Yang LI Ying LI Peng-yue CHEN Zhen-zhen |
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| Affiliation: | School of Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102, China;School of Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102, China;School of Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102, China;School of Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102, China;School of Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102, China;School of Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102, China |
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| Abstract: | The application state of pharmaceutical excipients hydroxy propyl methyl cellulose(HPMC) in preparation was introduced. The author referred to the related domestic and overseas literatures in recent years to carry out the analysis and induction, and described the application state of solid preparation, liquid pharmaceutical, sustained-controlled preparation, capsule formulations, gel preparation and bioadhension preparations. HPMC can be widely used and will play a key role in the field of pharmaceutical preparations. |
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| Keywords: | hydroxy propyl methyl cellulose pharmaceutical preparation pharmaceutical excipients |
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