| 腹泻小儿肠道双歧杆菌含量变化及临床意义 |
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| 引用本文： | 吴斌,温彩霞,黄妙辉,吴丽瑟,林旭,游开绍. 腹泻小儿肠道双歧杆菌含量变化及临床意义[J]. 福建医科大学学报, 1996, 0(2) |
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| 作者姓名： | 吴斌 温彩霞 黄妙辉 吴丽瑟 林旭 游开绍 |
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| 作者单位： | 福建医学院附属第一医院儿科，福建医学院基因工程研究室 |
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| 摘 要： | 目的研究患儿肠道双歧杆菌含量变化。方法定量检查６５例不同年龄健康儿童和６５例腹泻患儿肠道双歧杆菌含量。结果新生儿肠道双歧杆菌含量明显低于婴幼儿，１月～７岁小儿肠道双歧杆菌含量为１１．６９±０．３２ｌｏｇ１０ｎＣＦＵ／ｇ，各年龄组之间无显著差别。腹泻患儿肠道双歧杆菌含量明显下降（Ｐ＜０．０１）；恢复期明显上升，与急性期比较有显著差异（Ｐ＜０．０１），但仍低于健康对照组。急性肠炎患儿肠道双歧杆菌含量与患儿住院后止泻时间呈显著负相关（Ｐ＜０．０１）。结论双歧杆菌是小儿肠道正常菌群优势茵，其在小儿腹泻发生、发展过程中起重要作用；病情迁延与肠道双歧杆菌数量恢复慢有关。
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| 关 键 词： | 感染性腹泻.小儿，双歧杆菌 |
Changes and Clinical Significance of Fecal Bifidobacteria in Children with Diarrhea |
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| Wu Bin,Wen Caixia, Huang Miaohui,et al. Changes and Clinical Significance of Fecal Bifidobacteria in Children with Diarrhea[J]. Journal of Fujian Medical University, 1996, 0(2) |
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| Authors: | Wu Bin Wen Caixia Huang Miaohui et al |
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| Abstract: | Objective To study the change of bifidobacteria in fecal for health and diarrhea children. Methods The levels of bifidobacteria in fecal from 65 children's diarrhea and 65 health controls were observed.Results The amount of fecal bifidobacteria in newborn was significantly lower than that of children over 1 month,but there were no significant difference among infant and preschool children. The bifidobacteria amounts were descended in acute stage of diarrhea and increased in recovery.There were a negative relationship between the bifidobacteria amounts and the disappear time of diarrhea symptom after hospitalization.Conclusion The bifidobacteria was predominate in intestinal flora of children and play an important roles in diarrhea. |
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| Keywords: | diarrhea children bifidobacteria |
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