Thirteen-year follow up of isolated foveal retinoschisis in a 24-year-old woman |
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Authors: | Chen Fred K McAllister Ian L Chelva Enid S |
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Affiliation: | Department of Ophthalmology, Royal Perth Hospital, Perth, Western Australia, Australia. |
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Abstract: | Foveal retinoschisis is rarely found in women. An 11-year-old girl, from non-consanguineous parents, presented with bilateral visual loss from isolated foveal retinoschisis as confirmed by a normal fluorescein angiogram and characteristic optical coherence tomogram. Psychophysical and electrophysiological studies demonstrated mild contrast sensitivity loss, dyschromatopsia and normal full field electroretinographic responses. Visual acuity, foveal retinoschisis, electroretinography, electro-oculography and visual evoked responses remained stable after 13 years but a reduction in pattern electroretinography amplitude was noted. No mutation was found in the coding regions of the RS1 gene. Isolated foveal retinoschisis may be a form of macular dystrophy. Longer-term follow up may contribute to our understanding of this rare disease. |
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Keywords: | electrophysiology genetic disorder optical coherence tomography retinoschisis. |
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