| 直缘乌头根中生物碱成分的研究 |
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| 引用本文： | 陈东林,简锡贤,王锋鹏.直缘乌头根中生物碱成分的研究[J].华西药学杂志,2002,17(5):326-328,331. |
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| 作者姓名： | 陈东林 简锡贤 王锋鹏 |
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| 作者单位： | 四川大学华西药学院,四川,成都,610041 |
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| 基金项目： | 国家博士点基金项目 (批准号:2 0 0 10 6 10 0 4 7) |
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| 摘 要： | 目的：研究直缘乌头（Aconitum transsectum Diels.）根中的生物碱成分。方法：采用pH梯度、中压柱层析、常压硅胶柱层析及离心薄层层析法。结果：分得11个已知二萜生物碱，由光谱法分别鉴定为：滇乌碱（yunaconitine）、印乌碱（indaconitine）、黄草乌碱甲（vilmorrianine A）、黄草乌碱丙（vilmorrianine C）、草乌甲素(crassialine A)、膝乌碱（geniconitine）、查斯曼宁（chasmanine）、８－去乙酰滇乌碱（8-deacetylyunaconitine）、塔拉萨敏（talatisamine）、14-乙酰塔拉萨敏（14-acetyltalatisamine）和chasmaconitine。结论：黄草乌碱甲和chasmaconitine是首次从该植物中分离得到。
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| 关 键 词： | 直缘乌头 C19－二萜生物碱 成分研究 |
| 文章编号： | 1006-0103(2002)05-0326-04 |
C19-DITERPENOID ALKALOIDS FROM ACONITUM TRANSSECUTUM DIELS. |
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| CHEN Dong-lin,JIAN Xi-xian,WANG Feng-peng West China School of Pharmacy,Sichuan University,Chengdu ,China.C19-DITERPENOID ALKALOIDS FROM ACONITUM TRANSSECUTUM DIELS.[J].West China Journal of Pharmaceutical Sciences,2002,17(5):326-328,331. |
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| Authors: | CHEN Dong-lin JIAN Xi-xian WANG Feng-peng West China School of Pharmacy Sichuan University Chengdu China |
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| Institution: | CHEN Dong-lin,JIAN Xi-xian,WANG Feng-peng West China School of Pharmacy,Sichuan University,Chengdu 610041,China |
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| Abstract: | OBJECTIVE To isolate C 19 diterpenoid alkaloids from the residue of the Crassialine A being industrially extracted from Aconitum transsecutum Diels.METHODS The isolation method were pH gradient extraction, MPLC, chromatotron and silica column chromatography. The structures are identified on the basis of spectral data. RESULTS Eleven known C 19 diterpenoid alkaloids yunaconitine, indaconitine, vilmorrianine A, vilmorrianine C. crassialine A, geniconitine, chasmanine, 8-deacetylyunaconitine, talatisamine, 14-acetyltalatisamine and chasmaconitine were isolated.CONCLUSION Vilmorrianine A and chasmaconitine were isolated from the Aconitum transsectum Diels. for the first time. |
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| Keywords: | Aconitum transsecutum Diels C 19 -diterpenoid alkaloids Component analysis |
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