| NCAM在大鼠不同发育时期视神经和坐骨神经中表达 |
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| 引用本文： | 孙建华,朱益华,朱捷,唐宝丰,徐国兴,韩晓丽,童绎.NCAM在大鼠不同发育时期视神经和坐骨神经中表达[J].中华现代眼科学杂志,2005,2(5):385-387,i0001. |
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| 作者姓名： | 孙建华 朱益华 朱捷 唐宝丰 徐国兴 韩晓丽 童绎 |
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| 作者单位： | [1]娄底市中心医院眼科,湖南娄底417000 [2]福建医科大学附属第一医院眼科,福建福州350005 [3]南平市第一医院眼科,福建南平353000 |
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| 基金项目： | 福建省科技厅重大科研项目（2000F005）. |
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| 摘 要： | 目的 观察神经细胞黏附分子（NCAM）在大鼠不同发育时期视神经及坐骨神经上的表达，探讨NCAM在视神经与坐骨神经分布的差异。方法 50只SD大鼠，按出生后天数分成5组，取部分视神经和坐骨神经，免疫组织化学方法和计算机图像分析技术，测定大鼠视神经和坐骨神经NCAM表达。结果 NCAM在不同年龄大鼠视神经和坐骨神经均见表达。坐骨神经表达水平高于视神经。出生后7天组明显高于其他年龄组。结论 大鼠视神经和坐骨神经NCAM表达差异有显著性。
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| 关 键 词： | 神经细胞黏附分子 视神经 坐骨神经 免疫组织化学 大鼠 |
| 文章编号： | 1681-6412（2005）05-0385-03 |
Expression of NCAM in the optic nerve and sciatic nerve of rats |
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| SUN Jian-hua, ZHU Yi-hua, ZHU Jie,et al..Expression of NCAM in the optic nerve and sciatic nerve of rats[J].Chinese Journal of Modern Eye Ear Nose and Throat,2005,2(5):385-387,i0001. |
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| Authors: | SUN Jian-hua ZHU Yi-hua ZHU Jie |
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| Institution: | Ophthalmology Department, Loudi City Centre Hospital, Loudi 417000, China |
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| Abstract: | Objective To investigate the expression of NCAM in the optic nerve and sciatic nerve of the rats during the different developing stages. Methods 50 SD rats were randomly divided into five groups. Both optic nerve and sciatic nerve were taken from them and determined the expression of NCAM by immunohistochemistry. The immunohistochemistry stainings were analyzed by automatic image analysis technology. Results The expression of NCAM in the sciatic nerve was higher than that in the optic nerve. The expression in the rats of 7days age was significantly higher than that in other groups. Conclusion The expression of NCAM in the optic nerve was significantly different from that of the sciatic nerve in the rats. |
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| Keywords: | neuronal cell adhesion molecule optic nerve sciatic nerve immunohistochemistry rat |
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