| 二尖瓣狭窄病人经皮球囊成形术前后血浆内皮素含量的变化 |
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| 引用本文： | 张春祥,范洪亮,修运强,曲鲁平,徐传金. 二尖瓣狭窄病人经皮球囊成形术前后血浆内皮素含量的变化[J]. 青岛大学医学院学报, 1993, 0(4) |
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| 作者姓名： | 张春祥 范洪亮 修运强 曲鲁平 徐传金 |
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| 作者单位： | 青岛医学院附属医院内科(张春祥，范洪亮，修运强，曲鲁平)，青岛医学院附属医院内科(徐传金) |
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| 摘 要： | 采用放射免疫方法测定38例风湿性心脏病二尖瓣狭窄病人经皮球囊成形术术前及术后1周时的血浆内皮素含量。术前病人的血浆内皮素含量较健康对照组显著升高(P<0.001),术后较术前显著下降(P<0.001),但仍高于对照组(P<0.002)。结果表明,二尖瓣狭窄病人的病理生理改变可引起血浆内皮素含量升高。监测术前及术后血浆内皮素的含量,有助于判定其疗效。
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| 关 键 词： | 二尖瓣狭窄 经皮球囊二尖瓣成形术 内皮素 放射兔疫测定 |
STUDY ON CHANGES OF PLASMA ENDOTHELIN BEFORE AND AFTER PERCUTANEOUS BALLOON MITRAL VALVULOPLASTY |
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| Zhang Chunxiang,Fan Hongliang,Xiu Yunqiang,et al. STUDY ON CHANGES OF PLASMA ENDOTHELIN BEFORE AND AFTER PERCUTANEOUS BALLOON MITRAL VALVULOPLASTY[J]. Acta Academiae Medicinae Qingdao Universitatis, 1993, 0(4) |
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| Authors: | Zhang Chunxiang Fan Hongliang Xiu Yunqiang et al |
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| Affiliation: | Zhang Chunxiang,Fan Hongliang,Xiu Yunqiang,et al Department of Medicin |
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| Abstract: | The plasma endothelin (ET) level was measured in 38 patients with mitral stenosisby a highly sensitive radioimmunoassay before and after percutaneous balloon mitralvalvuloplasty (PBMV). The results showed that the plasma ET level was significantlyhigher in patients before PBMV than in the control group (P<0.001). It decreased sig-nificantly after PBMV, but was still significantly higher than in the control group (P<0.002). The results suggest that ET may play a role in the pathophysiological processof rheumatic heart disease and mitral stenosis. Measuring the ET plasma level beforeand after PBMV may provide one of the parameters for evaluating the curative effect. |
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| Keywords: | wmitral stenosis peroutaneous ballon mitral valuloplasty endothelin radioimmunoassay |
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