华重楼中一个新的类胆甾烷皂苷

目的：从华重楼Paris polyphylla var.chinensis中分离活性成分皂苷类化合物。方法：药材用95％乙醇提取，提取物经D101大孔树脂柱，硅胶柱和ODS柱反复柱层析，得到化合物(1)。结果与结论：通过化学方法和波谱方法鉴定该化合物为一个新的类胆甾烷皂苷，命名为：Parispolyside E。该化合物结构为：3-氧-α-L-阿拉伯糖(1→4)[α-L-鼠李糖(1—2)]-β-D-葡萄糖-β-D—chacotriosyl-26-氧-β-D-葡萄糖苷，是在重楼属发现的第一个具有芳香环的类胆甾烷型的皂苷。

A new homo-cholestane glycoside from Paris polyphylla var.chinensis

AIM:Steroidal saponins were expected to be isolated from Paris polyphylla var.chinensis.METHOD:The plant material was extracted with 95% EtOH;the crude saponins were chromatographed on a D101,a silica gel and ODS column to afford the compound(Ⅰ).RESULT and CONCLUSION:On the basis of chemical methods and spectral evidences,compound(Ⅰ),named Parispolyside E,was confirmed as a new steroidal glycoside,possessing a homo-cholestane skeleton with an aromatized ring E.And its structure was characterized as 3-O-α-L-arabinofuranosyl (1→4)[α-L-rhamnopyranosyl(1→2)]-β-D-glucopyranosyl-β-D-chacotriosyl-26-O-β-D-glucopyranoside.