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中西医结合强化综合治疗原发性肝癌临床研究
引用本文:吕修臣,刘俊莉,张琼霞,郭军,孟爱国,王云涛,张志红,陈素强. 中西医结合强化综合治疗原发性肝癌临床研究[J]. 中国中西医结合急救杂志, 2001, 8(5): 306-308
作者姓名:吕修臣  刘俊莉  张琼霞  郭军  孟爱国  王云涛  张志红  陈素强
作者单位:1. 河北省邢台市第三医院
2. 河北省邢台市人民医院
基金项目:河北省邢台市自然科学基金资助项目(No.20014214)
摘    要:目的:观察超选择性肝动脉内强化化疗栓塞联合中药及免疫治疗原发性肝癌的疗效。方法:98例中晚期原发性肝癌患者随机分为对照组和强化综合治疗组各49例;分别进行单纯肝动脉内化疗栓塞和超选择性肝动脉内强化化疗栓塞联合中药及免疫治疗。结果:强化综合治疗组有效率(CR+PR)为91.9%(45/49),明显高于对照组59.2%(29/49),P<0.01。强化综合治疗组1、2、3年生存率分别为95.9%、83.6%和51.0%,中位生存期为21个月;而对照组分别为51.0%、34.7%和16.3%,中位生存期为11个月;2组比较均有非常显著性差异(P均<0.01)。白细胞计数在强化综合治疗组明显提高,对照组下降,2组有非常显著性差异(P<0.01)。结论:超选择性肝动脉内强化化疗栓塞联合中药及免疫治疗技术能明显提高肝癌患者近期治疗的有效率和生存率,增强机体免疫力,提高生存质量,为治疗肝癌的理想新技术。

关 键 词:中西医结合治疗 化疗栓塞 肝癌
文章编号:1008-9691(2001)05-0306-03
修稿时间:2001-02-26

Clinical study on treatment of primary hepatocarcinom a by intensive compositive integrated traditional Chinese and western medicine
Abstract:Objective:To study the effect of super selective therapeutic hepatic arterial carcinoma embolization combining with traditional herbal medicine.Methods:Ninetyeight cases of hepatic carcinoma on middle and advanced stage were randomly divided into control group and study group,49 cases each.The control group was given simple hepatic arterial embolism chemotherapy;study group was given super selective therapeutic hepatic arterial carcinoma embolism chemotherapy,Chinese herbal medicine and immunotherapy.Results:In study group,the effective rate(CR PR) was 91 9%(45/49),which was significantly higher than that of control group(59 2%,29/49, P <0 01).One,two and three year survival rate was 95 9%,83 6% and 51 0% respectively.The median length of survival was 21 months.In control group,one,two and three year survival rate was 51 0%?34 7% and 16 3% respectively.The median length of survival was 11 months.The differences in terms of these indices were significant(all P <0 01).White blood cell count in study group was higher after treatment,while the control group was lower,the difference was significant( P <0 01).Conclusions:This method can significantly elevate shortterm effective rate,survival rate,immunity and survival quality.
Keywords:integrated traditional Chinese and western medicine therapy  embolism chemotherapy  hepatic carcinoma  immune
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