软脉灵口服液质量标准研究

目的建立软脉灵口服液的质量标准。方法用薄层色谱法对处方中制何首乌、白芍、黄芪和淫羊藿进行定性鉴别；用高效液相色谱法测定制剂中丹酚酸B的含量。结果薄层色谱鉴别斑点清晰，专属性强。丹酚酸B在0．00pg～1．83旭范围内与峰面积呈现良好的线性关系，平均加样回收率为101．7％，RSD为1．5％。结论该法操作简便，结果可靠，重复性好，可用干软脉灵口服液的质量控制。

Study on quality standard for Ruanmailing oral Liquid

OBJECTIVE To establish the quality standard for Ruanmailing oral liquid. METHODS Radix polygoni multiflori praeparatacum succo glycines sotae, Radix paeoniae alba, Radix astragali and Herba epimedii in Ruanmailing oral liquid was identified by TLC; the content of salvianolic acid B in Ruanmailing oral liquid were determined by HPLC. RESULTS Radix polygoni multiflori praeparatacum succo glycines some, Radix paeoniae alba, Radix astragali and Herba epimedii could be detected. Salvianolic acid B showed a good linear relationship at the range of 0.04μg - 1.83μg, the average recovey of added sample was 101.7 % with RSD of 1.5 %. ODNCLUSION The method is simple with good reproducibility and can be used for control of Ruanmailing oral liquid.