Molecular Tissue Engineering: Applications for Modulation of Mesenchymal Stem Cells Proliferation by Transforming Growth Factor β_1 Gene Transfer |
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作者姓名: | 郭晓东 杜靖远 郑启新 刘勇 段德宇 吴永超 |
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作者单位: | GUO Xiaodong,DU Jingyuan,ZHENG Qixin,LIU Yong,DUAN Deyu,WU Yongchao Department of Orthopaedics,Xiehe Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022 |
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基金项目: | This project was supported by a grant from NationalNatural Science Foundation of China (No. 30 170 2 70 ) |
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摘 要: | It is well established that damaged articularcartilage has only a limited ability to healitself. Tissueengineering represents a new alternative approach tocartilage repairing. However,as it is very difficult toacquire seed cells with good activity,especially thoseinflammatory factors which induce the degradation ofarticular cartilage in the pathology of trauma orosteoarthritis were still exited,the success of all ofthese techniques has been variable and limited in thatnone were able to restore…
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关 键 词: | articular cartilage defect repair tissue engineering gene transfer mesenchymal stem cells transforming growth factor β 1 molecular tissue engineering |
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