Effect of Yiqitongyanghuatan Recipe on Experimental Atherosclerosis in Rabbits

Cardiac and cerebrovasculur disease is one of themost serious disease threatening human health and lifecurrently. Atherosclerosis is the main pathologicalbasis of ischemic heart disease and cerebrovasculardisease. So prevention of atherosclerosis is alsoprimary strategy for heart and cerebrovasculurdiseases. The etiology of atherosclerosis is blood stasisand phlegm retention in traditional Chinese medicine.However,blood stasis and stagnation of phlegm haveequivalent position in clinical treat…

Effect of Yiqitongyanghuatan recipe on experimental atherosclerosis in rabbits

In order to investigate the roles of Yiqitongyanghuatan (YQTYHT) recipe in reducing the levels of serum cholesterol and plasma lipid peroxidation(LPO), platelet aggregation function (PAgF) and platelet adhesion function (PAdF), the area of atherosclerotic plague coverage in aorta and the thickness of plague, 32 male Japanese white rabbits were divided into 4 groups. The results showed that the YQTYHT recipe could significantly lower the levels of serum cholesterol and tryglyceride, plasma LPO, and PAgF and PadF. The area of atherosclerotic plague coverage in aorta and the thickness of plague in the YQTYHT fed rabbits were decreased as compared with that in the high cholesterol fed rabbits. The above roles might contribute to the main mechanism of YQTYHT against atherosclerosis.