颈动脉粥样斑块与冠心病的相关性分析

目的 通过颈动脉内中膜厚度（IMT）的测定，探讨颈动脉粥样斑块与冠心病（CHD）的相关性。方法 非脑血管病患者60例分为对照组（13例均无冠心病史），心绞痛组（20例），心肌梗死组（27例）。冠心病诊断依据心电图，运动-静息^99mTc-MIBI心肌显像（SPEC）检查结果；颈动脉粥样斑块用多普勒超声诊断仪检测。结果 对照组颈动脉超声未见狭窄及粥样斑块，其颈动脉内膜厚度／腔内径〈0．1。心绞痛或心肌梗死组80％（38／47）发现存在颈动脉粥样斑块，颈动脉内膜厚度／腔内径〉0．1，收缩期颈内动脉血流速（IC）／颈总动脉血流速（CC）〉0．8，与对照组比较均有显著差异，但心绞痛组与心肌梗死组上述指标未见显著差异。结论 颈动脉粥样斑块与冠心病密切相关，可能是诊断冠心病的一个较好指标。

An analysis of relativity between carotid atheromatous plaque and coronary heart disease

Objective To study the relativity between carotid atheromatous plaque and coronary atherosclerotic heart disease (CHD). Methods 60 patients were divided into three groups: control (13 cases) , angina pectoral (20 cases) and myocardial infarction(27 cases) groups. The patients with CHD were confirmed by way of ECG and 99mTc-MIBI stress-rest myocardial perfusion SPECT. The carotid theromatous plague was established by poppler ultrasound. Results In the control group, the ultrasonic examination didn't show carotid artery stenosis and atheromtous ptaque and the thickness of internal membrane (TIM) of carotid/vascular cavity distance was <0. 1. In angina pectoral and rmyocardial infarction groups the carotid atheromatous plaques were found in 80% (38/47) of all the cases, the TIM of carotid/vessel cavity distance was>0. 1, IC/CC>0. 8. A significant difference is seen between CHD group and contrl group, but without significant difference between angina pectoral group and myocardial infarction group. Conclusion A close correlation existed between carotid atheromatous plaque and CHD, so the carotid atheromatous plaque might be as an effective parameter for diagnosis CHD.