生物材料创面敷料封闭负压引流在大面积创面植皮中的应用

背景：大面积创面植皮中封闭创面、减少渗出、避免难愈性伤口的出现是治疗中的关键,采用自主研发的新型生物材料创面敷料可以提高植皮成功率。目的：观察基于生物材料创面敷料封闭负压引流在大面积创面植皮应用中的疗效。方法：对于60例大面积创面植皮的患者采取志愿选择的方式,分为生物材料创面敷料组、合成敷料组及常规加压包扎组。敷料组患者清创邮票植皮后采用生物材料创面敷料、合成敷料覆盖,其外用生物半透膜封闭形成负压装置,或直接常规敷料加压包扎。常规敷料包扎组植皮后采用消毒油纱覆盖植皮创面、敷料加压包扎。植皮后1周创面的单位面积植皮覆盖率。结果与结论：采用负压引流能明显提高单位面积植皮覆盖率,单位面积植皮覆盖率生物材料创面敷料组高于合成敷料组(P < 0.05),显著高于常规组。结果表明,新型生物材料创面敷料能有效引流,提高封闭负压引流的疗效。关键词：创面敷料;生物材料;封闭负压引流术;植皮;植皮覆盖率doi:10.3969/j.issn.1673-8225.2012.03.037

Application of vacuum-sealing drainage based on wound surface dressing biomaterials in large area skin grafting

BACKGROUND: The key points of large area skin grafting are blocking wound surface, decreasing exudation and avoiding diff-healing wounds. A new wound surface dressing biomaterial can improve the achievement ratio of skin grafting.OBJECTIVE: To study the curative effect of vacuum-sealing drainage (VSD) based on wound surface dressing biomaterials on large area skin grafting.METHODS: Sixty patients with large area skin grafting were divided into three groups by their wishes: wound surface bio-dressing group, synthetic material group and routine pressure dressing group. Dressing group patients were covered by wound surface dressing biomaterials and synthetic materials after debridement and skin graft, and then biological semipermeable membrane was used to construct a vacuum device or routine pressure dressing directly. The coverage of skin grafting was calculated at one week after skin grafting.RESULTS AND CONCLUSION: The coverage of skin grafting was improved by using VSD. The coverage of skin grafting in the wound surface dressing biomaterial group was higher than that of the synthetic material group (P < 0.05). Compared with the routine pressure dressing group the coverage of skin grafting was significantly increased in the other two groups. New wound surface dressing biomaterials can improve the curative effect of VSD.