郑州市2006-2011年腹泻病人中沙门菌血清型和耐药谱分析

摘要：【目的】了解郑州市感染性腹泻病人中沙门病原菌血清型分布和耐药谱，为沙门菌防治提供基础数据。【方法】从2006-2011年腹泻病监测点感染性腹泻病例的粪便标本中进行沙门菌分离培养、血清学分型及药敏试验，用WHONET5.4软件分析药敏试验结果。【结果】2006-2011年共采集的3266份腹泻病人标本中共检出196株沙门菌，检出率为6.0%，分布于10个血清群，37个血清型；以B群和D1群为主，各占33.67%（66/196）和32.14%(63/196)；血清型以肠炎沙门菌和鼠伤寒沙门菌为主，各占29.59%（58株）和19.90%（39株）。药敏试验结果提示对氨苄西林、萘啶酸、复方新诺明和四环素的耐药率分别达到44.90%、42.34%、34.18%和32.14%。【结论】沙门菌血清型和耐药谱监测对感染性腹泻疫情防控意义重大。

Analysis the Serum type and Antibiotic Resistance of Salmonella from Infectious Diarrhea Cases during 2006-2011 in Zhengzhou

Abstract: Objective: To understand the serotype distribution and antibiotic resistance Salmonella from Infectious Diarrhea Cases, and to provide the scientific basics for diseases control and treatment. MethodsSalmonella were isolated from infectious diarrhea cases and tested for serotyping and antibiotic sensitivity during the 2006 to 2011. Results were analyzed by the WHONET5.4 software. Results196 isolates of salmonella were detected from 3266 diarrhea patients and distributed in 10 serogroups and 37 serotypes. The detection rate was 6.0%. There were about 66 isolates of them belong to serogroup B ( 33.67%) and 63 isolates were part of serogroup D1 ( 32.14%). The main serotypes were salmonella enteritis and salmonella typhimurium (29.59%, 58/196; 19.90%, 39/196). Antibiotic sensitivity tests showed the isolates resistance to nalidixic acid, ampicillin, tetracycline, and SXT, and the resistance rates were 42.34%、44.90% and 32.14% and 34.18%.ConclusionIt was significance to monitoring the serotypes and antibiotic resistance of Salmonella infectious for diarrhea epidemic prevention and control.