支原体检测与治疗对复发性外阴阴道假丝酵母菌病的作用

通过对复发性外阴阴道假丝酵母菌病(RVVC)患者同时进行支原体检测与相应治疗,探讨支原体感染对诱发RVVC中的作用。方法回顾性分析过去3年收治的250例诊断为RVVC患者,按随机数字表法分为实验组(100例)与对照组(150例),实验组入组同时行支原体检测及药敏试验,实验组RVVC合并支原体阳性者(实验1组)同时予常规抗真菌及抗支原体治疗,实验组RVVC合并支原体阴性者(实验2组)仅给予抗真菌治疗;对照组不检测支原体,治疗仅给予常规抗真菌治疗。结果实验组中,69%患者(69例)同时合并支原体感染,2者同时治疗后治愈率为92.75%(64例);实验组中支原体阴性者,治愈率为90.32%(28例);对照组治愈率为40.67%(61例)。实验1、2组与对照组治愈率比较差异有统计学意义(P<0.01)。结论支原体感染对诱发女性生殖道RVVC有一定作用,给予同时治疗可以降低RVVC复发率。更多还原

Role of Mycoplasma Detection and Treatment in Recurrent Vulvovaginal Candidiasis

Objective To investigate the role of mycoplasma infection in recurrent vulvovaginal candidiasis(RVVC) through the detection and treatment of mycoplasma.Methods Data of 250 patients diagnosed with RVVC in past 3 years were retrospectively analyzed.Theses patients were randomly divided into two groups.Patients in experimental group(n=100) underwent mycoplasma detection and drug susceptibility testing,and then mycoplasma positive RVVC patients were given conventional anti-fungal and anti-mycoplasma treatment and mycoplasma negative RVVC patients were only given anti-fungal treatment.The control group(n=150) only received conventional anti-fungal therapy.Results Among the 100 patients in experimental group,RVVC was complicated by mycoplasma infection in 69(69%),and clinical cure was achieved in 64(92.75%).Among mycoplasma negative RVVC patients,clinical cure was achieved in 28(90.32%).Among the 150 patients in control group,clinical cure was achieved in 61(40.67%).Experiment 1 and 2 compared with the control group the cure rate difference was statistically sigaificant(P<0.01).Conclusion Mycoplasma infection can induce RVVC.Simultaneous treatment of mycoplasma infection and RVVC can reduce recurrence of RVVC.