| 大鼠视交叉上核的生后发育变化 |
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| 引用本文： | 童毅爱,陈丽琏,谷华运,王有琪. 大鼠视交叉上核的生后发育变化[J]. 复旦学报(医学版), 1987, 0(4) |
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| 作者姓名： | 童毅爱 陈丽琏 谷华运 王有琪 |
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| 作者单位： | 上海医科大学基础医学部组织胚胎学教研室(童毅爱，陈丽琏，谷华运)，上海医科大学基础医学部组织胚胎学教研室(王有琪) |
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| 摘 要： | 用Golgi法研究大鼠视交叉上核(SCN)的生后发育,可分为两个阶段。第一阶段(新生至生后5d),神经元快速生长和分化,树突由粗短变为纤细,伴有串珠状膨大,丝状突起和生长锥,小棘始基出现。第二阶段(生后6～31d),神经元生长发育和成熟阶段,表现在串珠状膨大,丝状突起和生长锥的消长变化,小棘始基转变为蘑菇形结构。电镜观察结果,在生后三周内,神经元胞质进行性增加,细胞器逐渐丰富,第二周末突触数量显著增加,且形式多样。
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| 关 键 词： | 视交叉上核 生长锥 丝状突起 小棘 |
THE POSTNATAL DEVELOPMENT OF THE HYPOTHALAMIC SUPRACHIASMATIC NUCLEUS OF THE RAT |
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| Tong Yiai,Chen Lilian,Gu Huayun,Wang Youqi. THE POSTNATAL DEVELOPMENT OF THE HYPOTHALAMIC SUPRACHIASMATIC NUCLEUS OF THE RAT[J]. Fudan University Journal of Medical Sciences, 1987, 0(4) |
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| Authors: | Tong Yiai Chen Lilian Gu Huayun Wang Youqi |
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| Abstract: | Postnatal development of the supraehiasrnal ic nucleus (SON) in the rat wag studied under Golgi staining and was divided into 2 stages. In the first stage, from birth to postnatal day 5, the SON neurons grow and differentiate rapidly. Short, crude dondrites become fine and beaded with many filopodias and growth cones. Spino buds become visible from the fifth day. During the second stage, from postnatal day 5 to day 31, beaded dendrites with growth cones and filopodia gradually disappear and spine buds change into the adult mushroom type spine. Fine structure of the SCN cells shows that the cytoplasm, cell organelles and various synapses increase steadily becoming more obvious at the end of second week. These changws seem to be associated with opening of the eyes. |
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| Keywords: | suprachiasmatic nucleus growth cone filopodia spine |
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