Detection of human papillomavirus types 16 and 18 in the exfoliated cervical cells using the polymerase chain reaction. |
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| Authors: | A Nakazawa M Inoue J Saito T Sasagawa G Ueda O Tanizawa |
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| Affiliation: | Department of Obstetrics and Gynecology, Osaka University Medical School, Japan. |
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| Abstract: | We applied the polymerase chain reaction (PCR) to detect HPV 16 and 18 in cytological samples obtained from the uterine cervices of Japanese women. HPV infection was detected in 17 (25%) of 67 with CIN and 11 (37%) of 30 with cervical carcinoma. It is notable that 11 (16%) of 69 women with normal cervices were infected with either HPV 16 or 18. The polymerase chain reaction is sensitive and useful for epidemiological studies. |
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